ABOUT ME

Performing research activities in different areas of Nutritional Biochemistry. My focuss is on the emerging health morbidities in India such as Osteoporosis, Colon cancer, Obesity and role of Phytoestrogens as a therapeutic approach in the protection/prevention of health complications. And also working in the area of Lead toxicity and the role of Amyloid peptides in the Human brain cells.

Monday, April 13, 2015

Multifaceted Flax seed - Mine of Typical Nutrients


Flax seeds (also called linseeds) are a rich source of micronutrients, dietary fiber, manganese, vitamin B1, and the essential fatty acid alpha-linolenic acid, also known as ALA or omega-3. 
The seeds come from flax, one of the oldest fiber crops in the world - known to have been cultivated in ancient Egypt and China. But the wide use is observed in many parts of the word including India. The Latin name for flax is Linum usitatissimum, which means "the most useful".Flax is one of the easily cultivated crops that flourishes well both in tropical as well as subtropical climates, with its higher production as a field crop noted in some fertile river valleys. It is an erect annual plant growing about 1 to 1.5 meters tall and bears light-blue colored attractive flowers. Flax fruit pod is a round, dry capsule 6–9 mm diameter, containing several brown or golden-yellow seeds (depending on cultivar type). The seeds feature smooth, glossy surface and flat shape that somewhat appear like sesame seeds but quite larger, measuring about 5–7 mm in length. In general, there exist two common cultivars of flax; one is predominantly grown for its oil seeds and the other variety for fiber. Seed flax generally features brown, and yellow or golden-yellow color seeds, with most types having similar nutritional values and equal amounts of short-chain omega-3 fatty acids. King Charlemagne of the 8th century believed so strongly in the health benefits of flaxseed that he demanded his loyal subjects eat the seeds and passed laws to make sure of it!!!!
             Nutritive Composition of Flax seeds
Flax seeds (Linum usitatissimum),
Nutritional value per 100 g.
(Source: USDA National Nutrient database)
Principle
Nutrient Value
Percentage of RDA
Energy
534 Kcal
27%
Carbohydrates
28.8 g
22%
Protein
18.3 g
32.5%
Total Fat
42.16 g
170%
Cholesterol
0 mg
0%
Dietary Fiber
27.3 g
68%
Vitamins
Folates
87 µg
22%
Niacin
3.08 mg
19%
Pantothenic acid
0.985 mg
20%
Pyridoxine
0.473 mg
36%
Riboflavin
0.161 mg
12%
Thiamin
1.64 mg
137%
Vitamin A
0 IU
0%
Vitamin C
0.6 mg
1%
Vitamin E
19.95 mg
133%
Vitamin K
4.3 µg
3.5%
Electrolytes
Sodium
30 mg
2%
Potassium
813 mg
17%
Minerals
Calcium
255 mg
22.5%
Copper
1.12 mg
124%
Iron
5.73 mg
72%
Magnesium
392 mg
98%
Manganese
2.48 mg
108%
Zinc
4.34 mg
39%
Phyto-nutrients
Carotene-ß
0 µg
--
Lutein-zeaxanthin
651 µg
--
 Unique Nutrient Features of Flax seeds
  Ø The first unique feature of flax is its high omega-3 fatty acid content. Among all 127 World's Healthiest Foods, flaxseeds comes out number one as a source of omega-3s! The primary omega-3 fatty acid found in flaxseeds is alpha-linolenic acid, or ALA. The ALA in flaxseed has found to be stable for at least 3 hours of cooking at oven temperatures (approximately 300F/150C), which makes it available after ground flaxseeds have been added to baked goods like muffins or breads.
  Ø  The second unique feature of flaxseed is its lignans. Lignans are fiber-like compounds, but in addition to their fiber-like benefits, they also provide antioxidant protection due to their structure as polyphenols. Among all foods commonly eaten by humans, researchers rank flaxseeds as the number one source of lignans.
  Ø  A third unique feature of flaxseeds is their mucilage (gum) content. "Mucilage" refers to water-soluble, gel-forming fiber that can provide special support to the intestinal tract. For example, gums can help prevent the too rapid emptying of the stomach contents into the small intestine, thereby improving absorption of certain nutrients in the small intestine.
  Ø  This combination of features—omega-3 fatty acids, high-lignan content, and mucilage gums—is a key factor in the unique health benefits of flaxseeds.
Health benefits of Flax seed
  • As in other oil seeds, flax too is one of the very high-calorie foods. 100 g of seeds contain 534 calories or 27% of daily-required levels. Further, the seeds are an excellent source of numerous health-benefiting nutrients, dietary fiber (mucilage), minerals, antioxidants and vitamins that are essential for optimum health.
  • Flax seed is rich in monounsaturated fatty acids like oleic acid. It is also one of the top plant sources ofomega-3 essential fatty acids such as linoleic acid, alpha-linolenic acid (ALA) and arachidonic acids. Regular intake of small portions of flax seeds in the diet helps to lower total as well as LDL or “bad cholesterol” and increases HDL or “good cholesterol” levels in the blood. Research studies suggest that Mediterranean diet that is rich in fiber, monounsaturated fatty acids and omega-3 fatty acids help to prevent coronary artery disease and strokes by favoring healthy blood lipid profile.
  • Flax seeds are perhaps one of the most widely available botanical sources of n−3 or ω (omega)-3 fatty acids. Flax seed oil consists of approximately 55% ALA (α-linolenic acid). One spoonful of flax seed oil provides about 8 g of omega-3 fatty acids. Research studies have suggested that n-3 fatty acids by their virtue of anti-inflammatory action help lower the risk of blood pressure, coronary artery disease, strokes and breast, colon and prostate cancers. Adequate quantities of n-3 oils are required for normal infant development and maturation of nervous system.
  • The seeds contain lignans, a class of phytoestrogens considered to have antioxidant and cancer preventing properties.
  • Flax are an excellent source of vitamin E, especially rich in gamma-tocopherol; containing about 20 g (133% of daily-recommended values) per 100 g. vitamin E is a powerful lipid soluble antioxidant, required for maintaining the integrity of cell membrane of mucus membranes and skin by protecting it from harmful oxygen-free radicals.
  • The seeds are packed with many important B-complex groups of vitamins such as riboflavin, niacin, thiamin, pantothenic acid, vitamin B-6, and folates. Thiamin is an essential co-factor for carbohydrate metabolism and helps prevent beri-beri disease. Folates help prevent neural tube defects in the fetus when consumed during pre-conception period and pregnancy.
  • Furthermore, flax seed is rich source of minerals like manganese, potassium, calcium, iron, magnesium, zinc and selenium.
  • Flax or linseed oil has flavorful nutty aroma and has been used in cooking, and as “carrier" or "base oil” in traditional medicines and in pharmaceutical uses.
    Masala Idli

Cardiovascular Benefits

  Ø  When flaxseeds are consumed, two other omega-3 fatty acids have also been shown to increase in the bloodstream, namely, eicosapentaenoic acid (EPA) and docosapentaenoic acid (DPA). Increases in EPA and DPA also help provide inflammatory protection. Protection of our blood vessels from inflammatory damage is also provided by the lignans in flaxseeds. These lignans can inhibit formation of platelet activating factor (PAF), which increases risk of inflammation when produced in excessive amounts.
Ø  Risk of oxidative stress in the blood vessels can also be lowered by flaxseed intake. In addition to being a very good source of the mineral antioxidant manganese, polyphenols in flax seed—including flaxs eed lignans—provide measurable antioxidant benefits. The antioxidant benefits of one particular flax seed lignan, secoisolariciresinol, have been especially well-documented. Decreased lipid peroxidation and decreased presence of reactive oxygen species (ROS) in the bloodsteam have both been associated with flaxseed intake in amounts of approximately 2 tablespoons per day.
Ø  Intake of flax seeds has also been shown to decrease the ratio of LDL-to-HDL cholesterol in several human studies and to increase the level of apolipoprotein A1, which is the major protein found in HDL cholesterol (the "good" cholesterol). This HDL-related benefit may be partly due to the simple fiber content of flax seeds, since 2 tablespoons of ground flaxseed provide about 4 grams of dietary fiber.
Ø  Increased omega-3 fatty acid intake to help regulate blood pressure and to help reduce blood pressure in persons who have been diagnosed with hypertension. With its excellent content of the omega-3 fatty acid alpha-linolenic acid (ALA), flaxseed can definitely help us increase our overall omega-3 intake and, by doing so, decrease our risk of high blood pressure.

Antioxidant and Anti-Inflammatory Benefits

It is important to realize that the antioxidant and anti-inflammatory benefits of flaxseed do not apply only to the cardiovascular system. Oxidative stress (which is often related to deficient intake of antioxidant nutrients) and excessive inflammation (which can also be related to deficient intake of anti-inflammatory nutrients)  are common risk factors for a wide variety of health problems. These problems include development of insulin resistance, type 2 diabetes, asthma, obesity, and metabolic syndrome. There is preliminary evidence that flaxseed intake can decrease risk of all the problems above by increasing our anti-inflammatory and antioxidant protection.
Laddu
Cancer Prevention
The antioxidant and anti-inflammatory benefits of flax seeds also make them a logical candidate for cancer prevention. That's because chronic inflammation (even low level inflammation) and chronic oxidative stress are risk factors for cancer development. In the case of flax seeds, evidence of risk reduction is strongest for breast cancer, prostate cancer, and colon cancer. Breast cancer and prostate cancer are included in the list of cancers know as "hormone-related" cancers. Their risk reduction may be more closely related to flaxseed than risk reduction for other cancers due to the high lignan content of flaxseed especially three of the lignans found in flaxseeds—secoisolariciresinol, matairecinol, and pinoresinolThe lignans provided by flaxseed have also been shown to spark increased activity by certain Phase II detoxification enzymes that are responsible for deactivating toxins in the body. This support of the detox process may help prevent accumulation of toxins that might otherwise act as carcinogens and increase cancer risk. But, there are few reports indicates that, breast and prostate cancer patients should be more cautious in the frequency of consumption.

Digestive Health

The strong fiber content of flax seeds—including their mucilaginous fiber—help to delay gastric emptying and can improve intestinal absorption of nutrients. Flax seed fibers also help to steady the passage of food through our intestines. Finally, the lignans in flax seed have been shown to reduce risk of colon cancer

Flaxseeds and Post-Menopausal Symptoms

Post-menopausal benefits (such as reduction of hot flashes) and flax seed intake, with some studies showing significant benefits and also as it acts as a potential aid during management of perimenopausal and postmenopausal symptoms as well as during hormone replacement therapy (HRT). But, it may vary from one woman to another, it may turn out that flax seed intake is simply better at lessening menopausal symptoms in some women, and not as good at lessening symptoms in others.
Masala Chapathi

Side Effects and Warnings

  Ø  Flax seed should be ingested with adequate fluid intake (1:10 seed: liquid is suggested).
   Ø  Flax seed may lower blood sugar levels. Caution is advised in people with diabetes or hypoglycemia, and in those taking drugs, herbs, or supplements that affect blood sugar. Blood glucose levels may need to be monitored by a qualified healthcare professional.
Barfi
Ø  Flax seed may increase the risk of bleeding. Caution is advised in people with bleeding disorders or taking drugs that may increase the risk of bleeding. Dosing adjustments may be necessary.
Ø  Flax seed may cause low blood pressure. Caution is advised in people taking drugs or herbs and supplements that lower blood pressure.
Ø  Use cautiously in people with prostate cancer, high triglycerides, or hypothyroidism (underactive thyroid).
Ø  Use cautiously in women with hormone-sensitive conditions or women taking estrogens. Use cautiously pregnant or lactating women.
Ø   Avoid in people with known allergy or sensitivity to flax seed, flax seed oil, its  constituents.
Ø  Avoid in people with acute or chronic diarrhea, diverticulitis (colon disorder), or inflammatory bowel disease. Avoid use in open wounds or scraped surfaces.
Ø  Flax may also cause abdominal pain and bloating, altered estrogen activity, bowel obstruction, cell damage, change in bowel habits, decreased absorption of drugs.

Flax seed recipe 

     1.  Chutney podi / powder:visit http://indianhealthyrecipes.com/flax-seeds-podi- recipe/
     2. Seeds in Butter Milk : visit https://www.youtube.com/watch?v=NSVCRZtON1I
    3. Visit http://www.tarladalal.com/recipes-using-flax-seeds-1598 for 17 different kinds        of recipes